However, in a 2006 study, rats that were given microdoses of CBD spent less time asleep and more time awake during the test period.Small studies involving healthy human volunteers appear to mirror these findings.This suggests that insomnia sufferers are better off choosing strains with higher, potentially more sedating, levels of THC.The survey was relatively limited in scope, however, so additional research is required to confirm these findings.Since ancient times, cannabis has been used to address various maladies, including insomnia.More recently, however, the prohibition against cannabis has hampered serious scientific inquiry. Brazilian researchers, for example, have been conducting small human studies on the effects of cannabis—as well as its active constituents, THC and CBD—for decades.Among other findings, these investigators confirmed there is no “subjective or physical symptom” that would suggest any toxic effects from either acute or chronic doses of CBD.Likewise, in 2015, the influential Journal of the American Medical Association (JAMA) published a meta-analysis—an overview of multiple relevant studies—to arrive at several intriguing conclusions about the potential merits of cannabinoids for medicinal use.
CBD is credited with anti-anxiety, anti-psychotic, antidepressant, anticonvulsant, and neuroprotective activities in the body, among others. Rather, CBD has been shown to provide numerous benefits.
This paradoxical effect of CBD helps explain some of the misinformation regarding the perceived differences between the two types of cannabis: indica and sativa.