Non sedating antihistamine wiki


Medicines that are not totally essential should ideally be avoided during pregnancy, and pregnant women should not take antihistamines unless prescribed by a doctor.Antihistamines can be used in children though age limits do apply: hydroxyzine is not recommended for children under six months, and promethazine and alimemazine are not recommended for children under two years.The most commonly used ones are promethazine (Phenergan), hydroxyzine (Atarax), or alimemazine (Vallergan).



There are two different types of antihistamine – the older group, sedating antihistamines, can enter the brain and cause drowsiness, while the newer non-sedating antihistamines do not.Histamine-1 receptors are located in the airways, blood vessels and gastrointestinal tract (stomach and esophagus).Histamine-1 receptors are also found in the brain and spinal cord.Antihistamines are very good at relieving symptoms of an allergic reaction, such as: First-generation antihistamines were developed more than seventy years ago and are still in widespread use today.